SrasV1, Main, Exploration, bibRecord, 004E46

Detection of severe acute respiratory syndrome coronavirus RNA in plasma during the course of infection

Identifieur interne : 004E46 ( Main/Exploration ); précédent : 004E45; suivant : 004E47

Detection of severe acute respiratory syndrome coronavirus RNA in plasma during the course of infection

Auteurs : Wei-Kung Wang [Taïwan] ; Chi-Tai Fang [Taïwan] ; Hui-Ling Chen [Taïwan] ; Chao-Fu Yang [Taïwan] ; Yee-Chun Chen [Taïwan] ; Mei-Ling Chen [Taïwan] ; Shey-Ying Chen [Taïwan] ; Jyh-Yuan Yang [Taïwan] ; Jih-Hui Lin [Taïwan] ; Pan-Chyr Yang [Taïwan] ; Shan-Chwen Chang [Taïwan]

Source :

Journal of clinical microbiology : (Print) [ 0095-1137 ] ; 2005.

RBID : Pascal:05-0143513

Descripteurs français

KwdFr :
- ARN viral (sang), Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, RT-PCR, Sujet âgé, Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (physiopathologie), Syndrome respiratoire aigu sévère (virologie), Taïwan, Virus du SRAS (génétique), Virus du SRAS (isolement et purification).
MESH :
- diagnostic : Syndrome respiratoire aigu sévère.
- génétique : Virus du SRAS.
- isolement et purification : Virus du SRAS.
- physiopathologie : Syndrome respiratoire aigu sévère.
- sang : ARN viral.
- virologie : Syndrome respiratoire aigu sévère.
Pascal (Inist)
- Adulte, Adulte d'âge moyen, Coronavirus, Détection, Femelle, Humains, Microbiologie, Mâle, RT-PCR, Sujet âgé, Syndrome respiratoire aigu sévère, Taïwan.
Wicri :
- geographic : Taïwan.

English descriptors

KwdEn :
- Adult, Aged, Coronavirus, Detection, Female, Humans, Male, Microbiology, Middle Aged, RNA, Viral (blood), Reverse Transcriptase Polymerase Chain Reaction, SARS Virus (genetics), SARS Virus (isolation & purification), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (physiopathology), Severe Acute Respiratory Syndrome (virology), Severe acute respiratory syndrome, Taiwan.
MESH :
- chemical , blood : RNA, Viral.
- geographic : Taiwan.
- diagnosis : Severe Acute Respiratory Syndrome.
- genetics : SARS Virus.
- isolation & purification : SARS Virus.
- physiopathology : Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Adult, Aged, Female, Humans, Male, Middle Aged, Reverse Transcriptase Polymerase Chain Reaction.

Abstract

We examined severe acute respiratory syndrome-associated coronavirus (SARS-CoV) RNA in plasma of 32 patients (probable SARS cases) by a quantitative real-time reverse transcription-PCR assay and reported that the highest detection rate, 75%, was found between day 5 and day 7 of illness, followed by rates of 64, 50, and 38% found between day 8 and day 11, day 2 and day 4, and day 12 and day 16, respectively. Analysis of sequential SARS-CoV load in plasma from six cases revealed different patterns of viremia, with the peak between day 4 and day 8. Our findings of the high detection rate of SARS-CoV RNA in plasma before day 11, together with the relative convenience of collecting and handling plasma, suggest that plasma can be used for early diagnosis of SARS.

Affiliations:

Taïwan

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Coronavirus</term>
<term>Detection</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Microbiology</term>
<term>Middle Aged</term>
<term>RNA, Viral (blood)</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (isolation & purification)</term>
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<term>Severe Acute Respiratory Syndrome (physiopathology)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
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<term>Taiwan</term>
</keywords>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
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<term>Humains</term>
<term>Mâle</term>
<term>RT-PCR</term>
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<term>Syndrome respiratoire aigu sévère (virologie)</term>
<term>Taïwan</term>
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</keywords>
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</keywords>
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<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Coronavirus</term>
<term>Détection</term>
<term>Femelle</term>
<term>Humains</term>
<term>Microbiologie</term>
<term>Mâle</term>
<term>RT-PCR</term>
<term>Sujet âgé</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Taïwan</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Taïwan</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We examined severe acute respiratory syndrome-associated coronavirus (SARS-CoV) RNA in plasma of 32 patients (probable SARS cases) by a quantitative real-time reverse transcription-PCR assay and reported that the highest detection rate, 75%, was found between day 5 and day 7 of illness, followed by rates of 64, 50, and 38% found between day 8 and day 11, day 2 and day 4, and day 12 and day 16, respectively. Analysis of sequential SARS-CoV load in plasma from six cases revealed different patterns of viremia, with the peak between day 4 and day 8. Our findings of the high detection rate of SARS-CoV RNA in plasma before day 11, together with the relative convenience of collecting and handling plasma, suggest that plasma can be used for early diagnosis of SARS.</div>
</front>
</TEI>
<affiliations><list><country><li>Taïwan</li>
</country>
</list>
<tree><country name="Taïwan"><noRegion><name sortKey="Wang, Wei Kung" sort="Wang, Wei Kung" uniqKey="Wang W" first="Wei-Kung" last="Wang">Wei-Kung Wang</name>
</noRegion>
<name sortKey="Chang, Shan Chwen" sort="Chang, Shan Chwen" uniqKey="Chang S" first="Shan-Chwen" last="Chang">Shan-Chwen Chang</name>
<name sortKey="Chen, Hui Ling" sort="Chen, Hui Ling" uniqKey="Chen H" first="Hui-Ling" last="Chen">Hui-Ling Chen</name>
<name sortKey="Chen, Mei Ling" sort="Chen, Mei Ling" uniqKey="Chen M" first="Mei-Ling" last="Chen">Mei-Ling Chen</name>
<name sortKey="Chen, Shey Ying" sort="Chen, Shey Ying" uniqKey="Chen S" first="Shey-Ying" last="Chen">Shey-Ying Chen</name>
<name sortKey="Chen, Yee Chun" sort="Chen, Yee Chun" uniqKey="Chen Y" first="Yee-Chun" last="Chen">Yee-Chun Chen</name>
<name sortKey="Fang, Chi Tai" sort="Fang, Chi Tai" uniqKey="Fang C" first="Chi-Tai" last="Fang">Chi-Tai Fang</name>
<name sortKey="Lin, Jih Hui" sort="Lin, Jih Hui" uniqKey="Lin J" first="Jih-Hui" last="Lin">Jih-Hui Lin</name>
<name sortKey="Wang, Wei Kung" sort="Wang, Wei Kung" uniqKey="Wang W" first="Wei-Kung" last="Wang">Wei-Kung Wang</name>
<name sortKey="Yang, Chao Fu" sort="Yang, Chao Fu" uniqKey="Yang C" first="Chao-Fu" last="Yang">Chao-Fu Yang</name>
<name sortKey="Yang, Jyh Yuan" sort="Yang, Jyh Yuan" uniqKey="Yang J" first="Jyh-Yuan" last="Yang">Jyh-Yuan Yang</name>
<name sortKey="Yang, Pan Chyr" sort="Yang, Pan Chyr" uniqKey="Yang P" first="Pan-Chyr" last="Yang">Pan-Chyr Yang</name>
</country>
</tree>
</affiliations>
</record>

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Detection of severe acute respiratory syndrome coronavirus RNA in plasma during the course of infection

Detection of severe acute respiratory syndrome coronavirus RNA in plasma during the course of infection

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